This is a research study to learn if our new telehealth coaching program called WeLNES-GLP will help people maintain weight loss after they stop taking GLP-1s.

This study is for adults (18+) who:

• Currently take a GLP-1 medication for weight loss
• Plan to stop taking the GLP-1 in the next four to six weeks
• Live in the U.S.
• Can read English
• Have a smartphone
• Are willing to get on a scale
• Want to start a weight loss maintenance program in the next 30 days!

Enrollment:

1. Fill out a short online survey (5-10 minutes) to find out if you are eligible to join.
2. If you are eligible, you will have 1 week to fill out another online survey (30-40 minutes) about you and your experiences with GLP-1s and weight loss/maintenance.
3. You will then have 1 week to set up an online account and authorize WeLNES to share your weight data.
4. You will receive a phone call from us to answer a few questions to confirm your participation.
5. You'll be randomly assigned (like tossing a coin) to 1 of 2 telephone coaching programs. Both programs provide:
   • 16 telephone coaching calls in 16 weeks
   • Digital body weight scale

During the study:

• Complete weekly coaching calls for 16 weeks (4 months). The first call is 30-40 minutes, and the rest are 15-25 minutes each.
• Fill out follow-up surveys (20-30 minutes each) after 16 weeks (4 months) and 24 weeks (6 months).
  • You can do them online, by phone, or by mail.
  • Get up to $40 for each follow-up survey: $20 for completing the survey and saving your scale weight in the digital app + $20 bonus for completing the survey and weigh-in within 72 hours of when the survey link is emailed to you.
• After you finish your 16 calls and 2 follow-up surveys, you may be randomly selected to do a phone interview (45-60 minutes) asking about your experiences with the WeLNES-GLP program. If selected, you will receive an additional $50 for completing the interview.

Participation takes place over 6 months:

• Complete 16 calls with a telephone coach over 16 weeks (4 months). Calls are usually 15-25 minutes each.
• Complete 2 surveys (after 16 and 24 weeks), which take about 20-30 minutes.
• If you are selected to do a phone interview after finishing the calls and surveys, doing the interview should take about 45-60 minutes.

Yes! You will get:

• 16 weeks of free telehealth coaching to help maintain weight loss after stopping a GLP-1
• Digital body weight scale
• Up to $80 if both follow-up surveys and scale weigh-ins are completed
• An additional $50 if the phone interview is completed (if you are selected to do the phone interview about the program)

Both programs (you’ll be assigned to one) aim to help you learn how to maintain weight loss, manage nutrition, and increase exercise while stopping a GLP-1, but the type of information taught is different between the programs.

Everyone in the study, no matter which program you are assigned to, will get guidance on maintaining weight loss, nutrition, and exercise. Everyone in the study will get a free digital body weight scale.

1. Your contact information (name, phone number, email) is kept apart from all of your survey information
2. This website is encrypted for privacy and protection
3. This site's server (where all of the site's information is kept) is protected by a hardware firewall (another level of security)

Please see our privacy policy for more information.

Fred Hutchinson Cancer Center is a world leader in research to prevent, detect, and treat cancer and other life-threatening diseases. Our world-renowned researchers have received three Nobel Prizes and many other major awards. We're located in Seattle, Washington.

The study was created by scientists at Seattle's Fred Hutch Cancer Center. Our lead investigator is Dr. Jonathan Bricker, a scientist who specializes in healthy behavior change. He is a Full Professor at the Fred Hutch Cancer Center and Affiliate Professor at the University of Washington.